Unlike traditional column chromatography glassware, these flash chromatography units are automated and use pressure and force on yThe sample through the column (which is already packed with packing material).
As the mobile phase works through the column, it will only pull out certain molecules, while leaving others behind (due to how closely the solvents match the molecules’ polarity).
Faster, easier, and way more efficient.
These machines represent a tremendous advantage over column chromatography, in part because they have a digital read out from the built-in UV detector, which allows you to see what peaks are being produced. This readout lets you see what’s eluting or coming out of yThe column first. This way you can separate what you want more efficiently than ever before.
Sometimes referred to as low-pressure liquid chromatography, flash chromatography auto deposits samples into the machine. If you used traditional glass, on the other hand, you would have to sit there and move test tubes each time one filled up, wasting time.
Accurate & reliable – welcome to the future.
You can purify synthesis reaction mixtures, proteins, peptides, and natural extracts – from milligram to gram quantities.
The Iquat Gradient HPLC pump has a 1% accuracy, making for an efficient mixture of gradients within the unit.
You can also avoid “pre-mixing” the mobile phase with this machine.
Features:
two models available: 420 & 800
accepts varying size collection tubes – You can select the correct volume and size for yThe runs.
accepts flash chromatography columns from F0001 up to F0330, as well as prep LC columns (depending on model chosen)
UV Diode Array Detector – for accurate and repeatable results (with respect to compound peaks) while performing a run
multiple collection racks
full, touch-screen display
Not only that, but during a run, the instrument will generate a chromatogram for use in recognizing retention time and concentration of compounds against known standards
Our clients look to us to provide reliable and efficient solutions.
★★★★★
SafeLeaf has always been great at sourcing our unique needs, Sean and the team are awesome.
Brent
Operations Manager
★★★★★
The team at Safe Leaf is very knowledgeable and helpful. I can't recommend them enough if you're in this space and need someone you can trust to help you solve whatever your problem is.
Lincoln
CEO/CTO — BC Extraction Facilty
★★★★★
Safe Leaf came through for us in the design and build of our extraction facility. I couldn't have asked for a better quality service or source of knowledge and insight.
Mike H
Extraction Facility Operator
Common Questions
Frequently Asked.
SafeLeaf.ca carries a broad range of extraction and post-processing equipment including closed-loop hydrocarbon systems, CO₂ extractors, ethanol processors, rotary evaporators, falling film evaporators, wiped film distillation units, freeze dryers, vacuum ovens, and ancillary equipment. Browse the full catalogue or contact us for specific requirements.
Our primary market is Canadian processors. Some equipment can be sourced or referred for US-based operations, but regulatory and shipping considerations apply. Contact us to discuss your specific situation.
Yes. SafeLeaf.ca supports projects well beyond equipment sales, including planning, technical consulting, installation support, commissioning guidance, and broader turnkey implementation strategy.
Yes. Financing and leasing options may be available through partner channels, depending on the equipment package, customer profile, and project scope. This can make turnkey deployment much more accessible.
The best first step is a consultation. From there, SafeLeaf.ca can help define your extraction goals, recommend an appropriate workflow, identify compliance considerations, and shape a phased implementation plan.
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